See my post here..it may helpviewtopic.php?f=3&t=6023
Basically, you can crate your transform, then use the msitrans to make a new msi file with the settings.
This even can help with portal users...you create a new msi and place it in your client folder on the web server.
2x really needs to really improve on client settings and admin control. Esp for internal vs external users. (Even with the web portal)
(which other post and suggestion have been submitted)